SCU-MJ Authors instructions

Suez Canal University Medical Journal SCU-MJ

The Official Journal of Faculty of Medicine, Suez Canal University

Founded in 1998

The first image SCU teaching hospital
  1. SCU teaching hospital
  2. SCU teaching hospital

Current Issue Article, Volume 20, Issue 2, October 2017

Evaluation of Vitamin D Levels in Women with Carpal Tunnel Syndrome

Shaimaa M. Okasha*, Maii A. Abdel-latif, and Marwa Orabi


Background: For decades, the role of vitamin D was limited to the formation and maintenance of bone as well as homeostasis of calcium and phosphate. Vitamin D is a steroid molecule, mainly synthesized in the skin from 7 dehydrocholesterol by ultraviolet irradiation or obtained through the diet. The major circulating metabolite of vitamin D is 25(OH) Vitamin D (25(OH)D), with a half-life of 21–30 days. Serum concentration of 25(OH) D is the most reliable biochemical index of vitamin status. Aim: The goal of the present study was to investigate the relationship between vitamin D levels and carpal tunnel syndrome (CTS) Patients and Methods: This study included 50 female patients with mild to moderate CTS and assessed their serum 25-hydroxyvitamin D levels. We included patients with a diagnosis of CTS based on both the clinical symptoms and positive neurophysiology. Controls (electrophysiological negative symptomatic patients) were evaluated 50 patients matched with sex and age clinically by a rheumatologist. Results: the mean age of patients with CTS symptoms and control group were 49.2 ± 10.6 (range 21–54) and 49.7 ± 10.6 (range 20–55), respectively, with no significant difference between the two groups (p = 0.534). Patients with CTS symptoms had significantly lower 25(OH) D levels compared to controls. There’s significance difference among the CTS patient regarding Boston Carpal Tunnel Questionnaire (BQ). Conclusion: a potential link between vitamin D status and the occurrence of CTS is suggested. Keywords: CTS, Vit. D, Boston Carpal Tunnel Questionnaire